Psychoactive drugs and mental illness. People want scientists to test illicit subjects for use

This article really grinds me gears. Why? Because its more of an opinion article than a scientific research article. I’ll get into it a bit with some quotes. Here’s the article link.

Let’s give mentally ill people drugs and see what they do!

Discovery of new psychiatric medication, whether for the treatment of depression, autism or schizophrenia, is at a virtual standstill. As just one example, the antidepressants on the market today are no more effective at reversing the mood disorder than those that first became available in the 1950s.


Mental patients 1950′s.


Mental patients 2000′s.

See a difference?

Autism isn’t generally treated with medication, and new medications are not at a standstill. Medications from the 1950′s are rarely used today, except in emergencies, or when all else has failed, and there are a lot of trial’s going on and new medications popping up all over the place. A lot of TCA’s from the late 1950′s (they were made in the 1950′s and approved later that decade) are being phased out and now used for pain management, for example, Elavil, is fantastic for fibromyalgia, but they still work.

SNRI’s were approved in 1994, with Effexor.

From another article:

There appears no significant difference in effectiveness between SSRIs and tricyclic antidepressants, which were the most commonly used class of antidepressants before the development of SSRIs. However, SSRIs have the important advantage that their toxic dose is high, and, therefore, they are much more difficult to use as a means to commit suicide. Further, they have fewer and milder side effects. Tricyclic antidepressant also have a higher risk of serious cardiovascular side effects, which SSRIs lack.

Okay, sure, tricyclics are good. SSRI’s sure are safer, though.

Before the 1950s, opioids, amphetamine, and methamphetamine were commonly used as antidepressants. Their use was later restricted due to their addictive nature and side effects

From the article

LSD, ecstasy (MDMA), psilocybin and marijuana have, for decades, been designated as drugs of abuse. But they had their origins in the medical pharmacopeia. Through the mid-1960s, more than 1,000 scientific publications chronicled the ways that LSD could be used as an aid to make psychotherapy more effective. Similarly, MDMA began to be used as a complement to talk therapy in the 1970s. Marijuana has logged thousands of years as a medicament for diseases and conditions ranging from malaria to rheumatism.

Yea, throughout the 1950′s-1970′s there was something called MKULTRA.

MKULTRA was the first thing I thought when I heard of this article, and LSD being used as a “psychiatric medication”.


Princeton on MKULTRA

These covert tests included subjecting the unwitting subjects to hallucinogenic drugs and other chemicals, among other things.


Basically, LSD was given to people as a “truth serum”. A few people died, not of overdose, but of suicide. One CIA officer jumped out of a window, and the truth was blacked out forever. (Remember, MKULTRA was never approved by the president). They wanted to find the Manchurian Candidate, the perfect spy who could be trained, during the Cold War. They experimented on normal citizens, prisoners, mental patients and other CIA officers.

Once Project MKUltra officially got underway in April, 1953, experiments included administering LSD to mental patients, prisoners, drug addicts and prostitutes, “people who could not fight back”, as one agency officer put it.[32] In one case LSD was administered to a mental patient in Kentucky for 174 days


Another technique investigated was connecting a barbiturate IV into one arm and an amphetamine IV into the other.[38] The barbiturates were released into the person first, and as soon as the person began to fall asleep, the amphetamines were released. The person would then begin babbling incoherently, and it was sometimes possible to ask questions and get useful answers.



Many victims of MKULTRA were in mental hospitals, even one in Montreal, Canada.


Other experiments involved drugs such as temazepam (used under code name MKSEARCH), heroinmorphineMDMAmescalinepsilocybinscopolaminemarijuanaalcoholsodium pentothal, and ergine (in Subproject 22)

Still think it’s a good idea? We do still use temazepam as a sleeping pill, but we use it carefully, with permission, and not in insanely high doses.

Anyone who has done MDMA, or ecstasy, knows that it will drive you to suicide the next day, or pretty close to it. If you look at brain scans of someone doing MDMA daily, it can literally cut holes in your brain.

cokeecstasy images

Neuroimaging (1st image) MDMA Basics (2nd image) Both Brain Scans of Brains on Drugs

“Despite its reputation as a relatively benign drug, data from animal and human studies suggest that MDMA may cause brain damage after just a few doses,unlike ‘harder’ drugs like cocaine and heroin, which take years to damage brain tissue.”  Link

I’ve tried Ecstasy, and in a more purer form, MDMA, at raves, and had a helluva day  the next day. I honestly wanted to kill myself, I crashed so hard. Not a good drug for the mentally ill, even if you’re taking your meds. Some people say, “well, take 5-HTP”, or “take an antidepressant as a booster the next day”. I did both, neither worked. I crashed hard, for days.

From the original article

these drugs are banned because they have no accepted medical use, but researchers cannot explore their therapeutic potential because they are banned. Three United Nations treaties extend similar restrictions to much of the rest of the world.

Well, there’s got to be a good reason for why they’re banned in most of the fucking world and not being used on psych patients! Sheesh.

Marijuana, I don’t have a problem with. We know it has medicinal values, mostly in the CNB, not the THC. It’s being legalized all over the US, and I’m Canadian. While not a user myself, and a strong hater of it in recreational form, I know it has benefits for many. As for LSD and MDMA, I see no benefit. This is just my opinion. I don’t think many mentally ill would benefit from LSD and MDMA, that they’ve been tested, given a chance, and shouldn’t even be categorized with marijuana. Period.

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