Daily Archives: August 16, 2017

Doctor Visit

SO I went to see Dr. Bishop this morning, and he was so pleased with my progress and getting a job and still going to school. SO that made me feel good.  I talked a bit about my concerns with my youngest child, and he said he would make a three-month appointment and see how that was doing.

I forgot to take any of my college stuff for my job so I didn’t do anything with that today.  I see Katrina tomorrow and will go either before or after that.  Get my ID made and my parking stickers.  I am still wrestling with the testing issue so I need to settle that out soon.

It’s always interesting to fill out the BASIC-32 whenever I go to the doctor  and see how my numbers have changed. I used to put down a lot of 2’s & 3’s ( moderate difficulty) then a lot of 1’s & 2’s (some  moderate difficulty).  Now it’s all 0’s and 1″s (minimal to no difficulty.).  It makes me proud every time I do it.

Hope everyone has a good rest of the week.  I know I will.


From CNN: Charlottesville victim’s mom: They tried to kill my child to shut her up

Right on, Mama!

Heather Heyer will not have died in vain.

http://www.cnn.com/videos/us/2017/08/16/susan-bro-mother-heather-heyer-memorial-service-bts.cnn


Gloom Mongered

Slept 4 and a half hours then woke, terrified I’d miss the alarm for my kid’s first day back to school cos, hello, smart phone, dumb Morgue…That anxiety ate away at me so I took .25mg of Xanax and right as the hamster wheel started to slow down…Spook-in-the-box pops up and can’t get back to sleep because she was nervous and excited about school. Which meant neither of us got back to sleep, she had her new clothes on and hair done by 5 a.m. I’d hoped even for a power nap but it didn’t happen then. I was relieved to drop her at school because her enthusiasm was killing me. Hypo and depression both HATE enthusiasm so it’s hard to know which cycle I am actually in.

The texting chihua got called back to his ‘real ‘ job, after working three days last week, then off two days, now he’s back and he was on me about the shop. And all I wanted was my first true kid free day in months and I texted back a little snarky, plus the bug treatment has me sweeping up corpses constantly before the cats can eat them and be poisoned…But because I do need his expertise with automobiles and of course, my heat will need fixed again come winter…I sucked it up and agreed to do four hours even though it pissed me off but the guilt was worse. I mean, he’s working two jobs and I’m gonna whine about a few hours of essentially sitting on my ass and occasionally helping hoist a TV in or out?

Guilt fucking sucks ass.

This morning I went home, feeling absolutely shitty from lack of sleep and finally when I got in the power nap…it lasted 20 minutes before my gloom spewing father called. And so my self esteem went further down the septic tank, my guilt skyrocketed, and my anxiety turned into an acid burning stomach ache. YAY. I dared defend the ONE good part of the ACA regarding pre-existing conditions and he launched into how he’s retired and still works and they take all his money to cover people who don’t pay taxes and (gee, who could he be pointing that finger at?) and he was up on his soapbox thumping his chest like the gloom mongering ass trash he is.

It isn’t that he doesn’t have a point. The system is broken and things need fixed. No one should shell out 70% of monthly income to have health insurance (which they can’t even use because it covers such a small percentage)…But hey, no soapbox here, my stomach is still churning from my dad’s preaching and guilting.

To add to it, new family drama. After the ugly split with my nephew and his fiance, I guess my sister moved in her stoner friends and the girl’s mother and they are all boo hooing over losing Medicaid cos my nephew turned 19 and isn’t in school and of course, the girl living with them is such a stoner she packs around selling weight and I don’t want my kid anywhere near it but then that starts war with my mom because hey, I drink alcohol, so it’s totally the same. Not to mention the sickly stoner’s mom is living in the living room with a porta potty right there so where is my kid supposed to play? With the porta potty or upstairs with the people holding pot or down in the basement smoking it?

So sick of the fucking drama. If I could just move far far away it wouldn’t be an issue. If I could just shake this fucking bipolar monkey and get a damned job and if my brain would just fucking behave and if, if, if…

Nothing like a good chat with dear old dad to bring the bad thoughts to the surface and remind me, apparently, even my own father considers me useless and I should just kill myself rather than his tax dollars pay for my disability because obviously there is nothing wrong with me EXCEPT I HAVE THE BRAIN FUNCTION OF A CARROT HALF THE TIME AND EITHER BURST INTO TEARS OR SARCASTIC ANGER OVER THE STUPIDEST SHIT! All a choice, of course, we all choose to feel this way. Because it’s fun and makes you feel good about yourself.

Bloody hell.

So in addition to being at the shop with a burning stomach ache, I can feel myself going down the rabbit hole which was tugging but thanks to dad, it’s yanking me downward.

I really want the mouse pad that is a target that says “bang head here.”


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Scientists Discover that the Immune System Controls Social Interaction

More amazing news, the immune system actually controls social behavior. It used to be thought that the immune system and the brain functioned independently of each other. However, that has been shown to be untrue. It has been shown that the immune system and the brain interact closely with each other and some of our behavior traits might have evolved because of our immune response to pathogens. “The relationship between people and pathogens, the researchers suggest, could have directly affected the development of our social behavior, allowing us to engage in the social interactions necessary for the survival of the species while developing ways for our immune systems to protect us from the diseases that accompany those interactions.”

Interferon γ, an immune molecule,  seems to be the molecule that is involved in both immune activity and how social organisms are! If interferon γ is knocked out in mice, they become much less social, and if it is restored, their social life gets better as well!

The theory is that even though we need to be social for survival, procreating, etc. being social increases our chances to get diseases. So interferon γ not only makes us more social but also protects us from getting sick.

And here are the amazing implications: “The researchers note that a malfunctioning immune system may be responsible for “social deficits in numerous neurological and psychiatric disorders.””

And: Litvak said. “Our findings contribute to a deeper understanding of social dysfunction in neurological disorders, such as autism and schizophrenia, and may open new avenues for therapeutic approaches.”

Incredibly amazing!

 

https://explorist.futurism.com/scientists-discover-immune-system-controls-social-interaction/
Health
Scientists Discover that the Immune System Controls Social Interaction
by explorist on July 19, 2017
Scientists Discover that the Immune System Controls Social Interaction
A Startling Discovery
In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects — and even controls — creatures’ social behavior, such as their desire to interact with others. So could immune system problems contribute to an inability to have normal social interactions? The answer appears to be yes, and that finding could have great implications for neurological conditions such as autism-spectrum disorders and schizophrenia.
“The brain and the adaptive immune system were thought to be isolated from each other, and any immune activity in the brain was perceived as sign of a pathology. And now, not only are we showing that they are closely interacting, but some of our behavior traits might have evolved because of our immune response to pathogens,” explained Jonathan Kipnis, PhD, chairman of UVA’s Department of Neuroscience. “It’s crazy, but maybe we are just multicellular battlefields for two ancient forces: pathogens and the immune system. Part of our personality may actually be dictated by the immune system.”
Evolutionary Forces at Work
It was only last year that Kipnis, the director of UVA’s Center for Brain Immunology and Glia, and his team discovered that meningeal vessels directly link the brain with the lymphatic system. That overturned decades of textbook teaching that the brain was “immune privileged,” lacking a direct connection to the immune system. The discovery opened the door for entirely new ways of thinking about how the brain and the immune system interact.
The follow-up finding is equally illuminating, shedding light on both the workings of the brain and on evolution itself. The relationship between people and pathogens, the researchers suggest, could have directly affected the development of our social behavior, allowing us to engage in the social interactions necessary for the survival of the species while developing ways for our immune systems to protect us from the diseases that accompany those interactions. Social behavior is, of course, in the interest of pathogens, as it allows them to spread.
The UVA researchers have shown that a specific immune molecule, interferon gamma, seems to be critical for social behavior and that a variety of creatures, such as flies, zebrafish, mice and rats, activate interferon gamma responses when they are social. Normally, this molecule is produced by the immune system in response to bacteria, viruses or parasites. Blocking the molecule in mice using genetic modification made regions of the brain hyperactive, causing the mice to become less social. Restoring the molecule restored the brain connectivity and behavior to normal. In a paper outlining their findings, the researchers note the immune molecule plays a “profound role in maintaining proper social function.”

Mikael Häggström/Wikimedia Commons
“It’s extremely critical for an organism to be social for the survival of the species. It’s important for foraging, sexual reproduction, gathering, hunting,” said Anthony J. Filiano, PhD, Hartwell postdoctoral fellow in the Kipnis lab and lead author of the study. “So the hypothesis is that when organisms come together, you have a higher propensity to spread infection. So you need to be social, but [in doing so] you have a higher chance of spreading pathogens. The idea is that interferon gamma, in evolution, has been used as a more efficient way to both boost social behavior while boosting an anti-pathogen response.”
Understanding the Implications
The researchers note that a malfunctioning immune system may be responsible for “social deficits in numerous neurological and psychiatric disorders.” But exactly what this might mean for autism and other specific conditions requires further investigation. It is unlikely that any one molecule will be responsible for disease or the key to a cure, the researchers believe; instead, the causes are likely to be much more complex. But the discovery that the immune system — and possibly germs, by extension — can control our interactions raises many exciting avenues for scientists to explore, both in terms of battling neurological disorders and understanding human behavior.
“Immune molecules are actually defining how the brain is functioning. So, what is the overall impact of the immune system on our brain development and function?” Kipnis said. “I think the philosophical aspects of this work are very interesting, but it also has potentially very important clinical implications.”
Findings Published
Kipnis and his team worked closely with UVA’s Department of Pharmacology and the group of Vladimir Litvak, PhD, at the University of Massachusetts Medical School. Litvak’s team developed a computational approach to investigate the complex dialogue between immune signaling and brain function in health and disease. “Using this approach we predicted a role for interferon gamma, an important cytokine secreted by T lymphocytes, in promoting social brain functions,” Litvak said. “Our findings contribute to a deeper understanding of social dysfunction in neurological disorders, such as autism and schizophrenia, and may open new avenues for therapeutic approaches.”
The findings have been published online in the journal Nature. The article was written by Filiano, Yang Xu, Nicholas J. Tustison, Rachel L. Marsh, Wendy Baker, Igor Smirnov, Christopher C. Overall, Sachin P. Gadani, Stephen D. Turner, Zhiping Weng, Sayeda Najamussahar Peerzade, Hao Chen, Kevin S. Lee, Michael M. Scott, Mark P. Beenhakker, Litvak and Kipnis.
This work was supported by the National Institutes of Health (grants No. AG034113, NS081026 and T32-AI007496) and the Hartwell Foundation.
This article was provided by  University of Virginia Health System. Materials may have been edited for clarity and brevity.


Transactivism is making a mockery of the fight against female genital mutilation

Female genital mutilation and surgical gender reassignment: do they have anything in common? Renee issues a passionate scholarly call to wake up and climb out of the PC muck. Please read and share and by all means follow Renee’s excellent blog!

writing by renee

About three years ago, Lisa Irwin, who identifies as a transwoman, travelled from New Zealand to Bangkok for gender reassignment operations. “I hoped that it would make me feel totally complete, as a “woman”,” says Lisa. “So I could get on with my life and start enjoying it.”

Things did not go according to plan.

the surgeon pretty much stuffed things up. Sometimes I can be sitting here and next thing it’s like someone’s got a knife and just starts stabbing me. I instantly knew it was wrong, it was kind of like I got hit by a big truck. I had to come back here to New Zealand, where there was nothing they could do for me.

Lisa now lives with daily pain, having experienced genital mutilation in the name of identity and medicine.

This experience was relayed earlier this year on a TV1 documentary called Born This Way

View original post 2,348 more words